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Principal Full Stack Engineer
full-timeCambridge$204k - $272k

Summary

Location

Cambridge

Salary

$204k - $272k

Type

full-time

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About this role

Your Impact at Lila


Join us in shaping the future of science! We are seeking an experienced full-stack senior software engineer to join our software platform team, where you’ll collaborate with software engineers, lab scientists, and machine learning engineers to build cutting-edge tools for automated scientific analysis and more. This role spans web services and data engineering, with a strong emphasis on Python development for scientific applications. If you thrive in a collaborative, fast-paced environment and bring best practices in git, development workflows, and user-centered design, we want to hear from you!


What You'll Be Building



  • Design & Build Services and Front-ends: Design and build high-performance, secure, and well-documented code that integrate with an ecosystem of existing services and apps.

  • Performance & Reliability: Diagnose and optimize system bottlenecks, ensuring high availability and low-latency performance across large-scale workloads.

  • Cloud & Infrastructure: Leverage AWS services, Kubernetes and modern DevOps practices to build and deploy production-grade systems at scale.

  • Cross-Functional Collaboration: Work with ML researchers, engineers, and scientists to integrate data pipelines, APIs, and cloud infrastructure into scientific workflows and services.


What You’ll Need to Succeed



  • Bachelor’s or Master’s degree in Computer Science, Engineering, or related field.

  • 4-8 years of experience writing software in a commercial setting.

  • Full Stack Development: Experience developing web apps across the full stack (React, TypeScript, Monorepos like Nx, TailWind, FastAPI, SQL/NoSQL, Python, Pydantic)

  • Cloud & DevOps Knowledge: Hands-on experience with AWS, GCP, or Azure; strong understanding of Kubernetes and containerization, infrastructure-as-code (Terraform, CloudFormation), and CI/CD pipelines (GitHub Actions).

  • Communication & Collaboration: Acute listening skills, and a proven track record of working cross-functionally with scientists, data engineers, and product teams; able to explain complex ideas to diverse audiences.

  • Problem Solving: Proven ability to take ownership of complex backend challenges, balancing trade-offs between scalability, performance, and maintainability.


Bonus Points For



  • Hands-On with Latest AI Tools: Exposure to AI technologies such as Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), or agentic frameworks, as well as experience leveraging AI to improve development performance.

  • Experience with ORMs: Experience with and web services for CRUD services (SQLModel, FastAPI, Django).

  • Orchestration Systems: Experience with orchestrators tools (Airflow, Prefect, Temporal, Dagster).

  • Familiarity with Python for Science: Familiarity with data science and ML libraries (pandas, numpy, scipy, jax, pytorch).

  • Domain Background: Exposure to laboratory software or analytics for life sciences, material sciences, or related fields.

  • Experience with laboratory devices, robotics, or hardware drivers. 


About Lila


Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science.  We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method.  We are introducing scientific superintelligence to solve humankind's greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before. Learn more about this mission at  www.lila.ai


If this sounds like an environment you’d love to work in, even if you only have some of the experience listed below, we encourage you to apply.


Compensation


We expect the base salary for this role to fall between $204,000-272,000 USD per year, along with bonus potential and generous early equity. The final offer will reflect your unique background, expertise, and impact.


We’re All In


Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.


Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.


A Note to Agencies


Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Other facts

Tech stack
Python,Full Stack Development,AWS,Kubernetes,DevOps,Collaboration,Problem Solving,AI Technologies,Data Engineering,Web Services,Cloud Infrastructure,User-Centered Design,Performance Optimization,Scientific Applications,CI/CD,Orchestration Systems

About Lila Sciences

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are building the foundation to apply AI to every aspect of the scientific method, enabling scientists to bring forth solutions in human health and sustainability at a pace and scale never experienced before.

Team size: 201-500 employees
LinkedIn: Visit
Industry: Technology, Information and Internet

What you'll do

  • Design and build high-performance, secure, and well-documented code that integrates with existing services and apps. Collaborate with cross-functional teams to integrate data pipelines and cloud infrastructure into scientific workflows.

Ready to join Lila Sciences?

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Frequently Asked Questions

What does Lila Sciences pay for a Principal Full Stack Engineer?

Lila Sciences offers a competitive compensation package for the Principal Full Stack Engineer role. The salary range is USD 204k - 272k per year. Apply through Clera to learn more about the full compensation details.

What does a Principal Full Stack Engineer do at Lila Sciences?

As a Principal Full Stack Engineer at Lila Sciences, you will: design and build high-performance, secure, and well-documented code that integrates with existing services and apps. Collaborate with cross-functional teams to integrate data pipelines and cloud infrastructure into scientific workflows..

Why join Lila Sciences as a Principal Full Stack Engineer?

Lila Sciences is a leading Technology, Information and Internet company. The Principal Full Stack Engineer role offers competitive compensation.

Is the Principal Full Stack Engineer position at Lila Sciences remote?

The Principal Full Stack Engineer position at Lila Sciences is based in Cambridge, Massachusetts, United States. Contact the company through Clera for specific work arrangement details.

How do I apply for the Principal Full Stack Engineer position at Lila Sciences?

You can apply for the Principal Full Stack Engineer position at Lila Sciences directly through Clera. Click the "Apply Now" button above to start your application. Clera's AI-powered platform will help match your profile with this opportunity and guide you through the application process. You can also learn more about Lila Sciences on their website.