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Foresite Labs (Stealth Co)

Staff Engineer, Systems & DevOps

full-time•San Diego•$175k - $185k

Summary

Location

San Diego

Salary

$175k - $185k

Type

full-time

Experience

10+ years

Company links

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About this role

Staff Engineer, Systems & DevOps

Location: San Diego, CA

Job Type: Full-Time

Pay Range: $175k - $185k

About Us

We are a venture-backed, stealth-stage biotechnology company based in San Diego, focused on developing novel technologies that will redefine how disease is detected, characterized, and managed with a novel approach to clinical genomics. Our mission is to fundamentally transform healthcare through a convergence of innovation across multiple scientific disciplines.

Founded by industry veterans with decades of experience in life sciences tools and diagnostics, our leadership team brings a proven track record of translating scientific insight into successful commercial products. Our investors include some of the most respected names in healthcare and deep tech.

Position Overview

We are looking for a Staff Systems & DevOps Software Engineer to own the infrastructure, configuration, and deployment foundations that keep our engineering teams productive and our systems reliable. This role will support both product software and internal test beds, and will work cross-functionally with firmware, hardware, HPC, and application engineers. You will help ensure that experimental systems, test infrastructure, and production deployments share consistent, debuggable, and well-managed software foundations.

This is a senior generalist role for an engineer who is comfortable operating across software deployment, system configuration, build and release pipelines, logging and observability, and Linux-based infrastructure. You will work closely with application, firmware, and HPC engineers to ensure software can be built, deployed, configured, monitored, and debugged consistently across development, test, and production environments. This role emphasizes pragmatic engineering over buzzwords: robust Linux systems, clear configuration practices, reliable deployments, and observability that actually helps engineers debug real systems.

Key Responsibilities

Systems & Deployment Engineering

  • Design and maintain systems for software configuration, deployment, and

    upgrades

  • Own deployment workflows across development, test, and production

    environments

  • Support software running in test beds, lab environments, and experimental

    systems

  • Manage system configuration using best practices for reproducibility and

    traceability

  • Support on-device, on-prem, and cloud-adjacent deployments as required

  • Work closely with engineering teams to operationalize new software components

Logging, Monitoring & Observability

  • Design and implement centralized logging and metrics collection

  • Ensure logs and metrics are structured, searchable, and useful for debugging

  • Build and maintain internal tooling for log visualization, exploration, and analysis

  • Work with engineers to improve log quality, signal-to-noise ratio, and

    debuggability

  • Deploy and manage observability tooling such as:

    • Prometheus

    • Grafana

    • Loki

    • Cloud-based storage such as S3

  • Define logging and monitoring standards across services, test beds, and deployed

    systems

  • Support alerting, diagnostics, and post-mortem analysis for deployed systems

Containerization & Runtime Environments

  • Build and maintain containerized environments for development and deployment

  • Define container build best practices and base images

  • Manage container runtimes and orchestration as appropriate to the system

  • Balance containerization with performance, debuggability, and operational

    simplicity

Linux Systems & Configuration Management

  • Administer and deeply understand Linux-based systems

  • Configure services, networking, storage, and security settings

  • Apply best practices for configuration management and system hardening

  • Debug system-level issues involving processes, filesystems, networking, and

    resource usage

Qualifications

Education:

 BS/MS in Computer Science or Engineering

Required:

Experience & Technical Skills

  • 7+ years of experience in systems, DevOps, or infrastructure-focused software

    roles

  • Strong, hands-on Linux expertise (administration, debugging, performance)

  • Experience designing and operating CI/CD and build pipelines

  • Solid understanding of logging, metrics, and observability best practices

  • Experience deploying and maintaining containerized systems

Programming & Tooling

  • Proficiency in at least one systems or scripting language:

    • C/C++

    • Python

    • Shell scripting

  • Ability to read, debug, and support production C/C++ and Python applications

  • Experience integrating build systems (e.g., CMake, Make, Bazel, etc.) into CI

    pipelines

  • Experience interfacing with cloud-based infrastructures (AWS, Azure, GCP)

    • IAM, Tiered Storage, EKS/Kubernetes, Databases etc.

Infrastructure & Observability

  • Experience with logging and monitoring stacks such as:

    • Prometheus/Granfana

    • Loki

    • S3 or similar object storage

  • Familiarity with cloud-adjacent tooling, even if systems are primarily on-prem or

    hybrid

Preferred:

  • Experience supporting embedded or HPC-adjacent systems

  • Familiarity with configuration management tools or infrastructure-as-code

    concepts

  • Experience operating systems in regulated or reliability-sensitive environments

  • Experience supporting distributed systems or edge deployments

Why Join Us

  • Work in a dynamic, collaborative environment where innovation and scientific rigor are

    deeply valued.

  • Join a seasoned and multidisciplinary team tackling high-impact problems at the

    intersection of science and engineering.

  • Competitive compensation and equity package, comprehensive benefits, and flexibility to support work-life integration.

Radian is an equal opportunity employer. We thrive on diversity and collaboration.

What you'll do

  • The Staff Engineer will design and maintain systems for software configuration, deployment, and upgrades while supporting software in various environments. This role emphasizes operationalizing new software components and ensuring reliable deployments across development, test, and production environments.

About Foresite Labs (Stealth Co)

Foresite Labs creates companies at the intersection of AI/machine learning and science. We believe AI, generative AI, and data science—when applied with scientific rigor—can accelerate discovery and drive innovations that benefit humanity. We provide the foundation for bold ideas to take shape and accelerate, shaping a better future for all. We offer competitive salaries, excellent benefits, and a flexible work environment where employees learn from top thinkers across multiple disciplines. With headquarters in San Francisco and Boston, we’re building a culture where scientific rigor meets entrepreneurial ambition. Foresite Labs Values Truth over progression: We follow the science, pursuing ideas that are grounded in data and abandoning them when not supported by the evidence. Take good risks: Our culture values informed risk-taking: good decisions are celebrated even when they result in bad outcomes. Everyone feels safe to contribute ideas and to learn from failure. Single accountable person: The project team lead is accountable for all decisions and for maintaining transparency and information flow within the team; we trust the project teams. The Review Committee unlocks capital and sets directions. Simplicity and Focus: “Companies die from indigestion, not starvation” (Bill Hewlett) We will focus on a few ideas aggressively and minimize all other distractions. Everyone will have a few key goals that have measurable outcomes. Respect and Community: Our employees are our greatest asset; everyone invests in creating an environment of collaboration and respect. We support their careers and career development whether they stay, go to a Labs company, or end up somewhere else.

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Frequently Asked Questions

What does Foresite Labs (Stealth Co) pay for a Staff Engineer, Systems & DevOps?

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Foresite Labs (Stealth Co) offers a competitive compensation package for the Staff Engineer, Systems & DevOps role. The salary range is USD 175k - 185k per year. Apply through Clera to learn more about the full compensation details.

What does a Staff Engineer, Systems & DevOps do at Foresite Labs (Stealth Co)?

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As a Staff Engineer, Systems & DevOps at Foresite Labs (Stealth Co), you will: the Staff Engineer will design and maintain systems for software configuration, deployment, and upgrades while supporting software in various environments. This role emphasizes operationalizing new software components and ensuring reliable deployments across development, test, and production environments..

Is the Staff Engineer, Systems & DevOps position at Foresite Labs (Stealth Co) remote?

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The Staff Engineer, Systems & DevOps position at Foresite Labs (Stealth Co) is based in San Diego, California, United States. Contact the company through Clera for specific work arrangement details.

How do I apply for the Staff Engineer, Systems & DevOps position at Foresite Labs (Stealth Co)?

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You can apply for the Staff Engineer, Systems & DevOps position at Foresite Labs (Stealth Co) directly through Clera. Click the "Apply Now" button above to start your application. Clera's AI-powered platform will help match your profile with this opportunity and guide you through the application process.
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