At Sequencing.com, we’re not just building a product - we’re transforming how people understand and improve their health through their DNA.

We’re looking for a Senior Backend Engineer to join our growing engineering team and help build the high-performance backend services that powers our core personalized experiences. You’ll work at the intersection of genomic data and production-scale AI, building the infrastructure that delivers intelligent, data-driven features to our users.

In this role, you’ll support and expand part of our core backend, collaborating closely with other senior engineers. You’ll help build, and maintain scalable infrastructure, APIs, and event-driven services. We’re looking for someone who thrives in fast-paced environments, takes ownership of complex problems, and writes clean, reliable code with performance and maintainability in mind.

Key Responsibilities

• Design, build, and maintain performant backend services in TypeScript

• Support and optimize production ready backend systems

• Integrate and manage services like PostgreSQL, MySQL, AWS SQS, and Centrifugo

• Collaborate with the lead AI backend engineer to intregate with our AI infrastructure

• Ensure high system reliability, security, and observability across services

• Own and drive end-to-end feature development with a strong eye on user experience

• Champion clean code, technical excellence, and continuous improvement

• Maintain, modernize, and migrate legacy code.

Requirements

• 5+ years of backend development experience

• Expert-level proficiency in TypeScript

• Experience with functional programming

• Deep experience with PostgreSQL, MySQL, and service based architectures

• Proven ability to work independently while collaborating closely with key teammates

• Passion for building systems that deliver exceptional customer experiences

• Strong debugging, testing, and performance-tuning skills

Bonus Points

• Familiarity with genomics, health data, or personalization systems

• Startup or fast-paced environment experience

• Familiar with Rust

• Work with OpenAI APIs and other AI frameworks to build intelligent, personalized user experiences

About Sequencing

Sequencing is powering the future of personalized health. We are the platform that transforms a person’s genome into a lifelong source of straightforward, actionable insights - for individuals, families, and healthcare professionals. By providing the application layer to your DNA, we turn complex genetic data into recurring value throughout every stage of life.

Our unique, clinical-grade Whole Genome Sequencing unlocks the most complete view of your DNA, screening for almost all known health conditions, traits, and medication responses - and translating that information into clear, actionable steps for managing health risks, optimizing wellness, and extending longevity.

As whole genome sequencing becomes a standard part of life, Sequencing is already the trusted platform where people safely store their DNA data - and will become the lifelong home for every genome on Earth. We’re a fully remote, global team of innovators, scientists, and builders, united by a mission to make genomics accessible, actionable, and life-changing for everyone. Proudly named GenomeWeb’s Best Place to Work in 2024, Sequencing is venture-backed and scaling rapidly to meet surging demand in the fast-growing personal genomics market. If you’re excited to help redefine how the world thinks about health, join us in building the platform that brings every genome to life.

Sequencing Inc. is an equal opportunity employer. All aspects of employment, including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.