About this role
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes.
The major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials. Upcoming studies are projected to include the analysis of samples from patients with type 1 diabetes participating in clinical trials, with trials expected to start in late 2023 and 2024. Additional studies involve analysis of samples from recipients of pancreas-kidney transplant in the context of recurrent type 1 diabetes.
As a successful candidate, you will:
· You must have experience with flow cytometry, molecular biology techniques, cell culture, microscopy, tissue processing, immunohistochemistry, immunofluorescence, data analysis (gene expression data, flow cytometry data, etc). While our research is primarily focused on human specimens, animal studies are used on occasion.
Your qualifications should include:
· PhD or M.D.
· Pre-doctoral experience/training in type 1 diabetes research desirable but not an absolute requirement
· Familiarity with computer software (Word, PowerPoint, Excel, databases) and basic statistical principles
Additional Information:
· For more information on nPOD please visit here: https://npod.org/
· For more information on the Arthur Riggs Diabetes & Metabolism Research Institute please visit here: https://www.cityofhope.org/research/riggs-institute/diabetes-milestones-and-history
· For more information on The Wanek Family Project for Type 1 Diabetes please visit here: https://www.cityofhope.org/research/riggs-institute/wanek-project/wanek-family-project-team
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.
Other facts
About City of Hope
City of Hope's mission is to deliver the cures of tomorrow to the people who need them today. Founded in 1913, City of Hope has grown into one of the largest cancer research and treatment organizations in the U.S. and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines, as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center at its core, City of Hope brings a uniquely integrated model to patients spanning cancer care, research and development, academics and training, and innovation initiatives. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. City of Hope’s affiliated group of organizations includes Translational Genomics Research Institute and AccessHope™.
What you'll do
- The successful candidate will engage in highly translational research focused on human type 1 diabetes, including investigating miRNA biomarkers and pancreas pathology. They will also analyze live pancreas tissue and samples from patients participating in clinical trials.
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